Police Scotland say that the male motorcyclist involved in the road accident on the A82 at Laggan Locks near Invergarry today, has sadly died.
Next of kin have been informed.
The accident involved a bus but neither the bus driver nor any passengers suffered any significant injuries.
The A82 is closed between Spean Bridge and Invergarry while crash investigators carry out a thorough examination of the scene.
Diversions are in place.
Enquiries into the full circumstances surrounding this incident are ongoing and anyone who can assist with the investigation is asked to contact Police Scotland on 101.